Combination drug
Tranylcypromine/trifluoperazine (brand names Parstelin , Parmodalin , Jatrosom N , Stelapar ) is a combination formulation of the monoamine oxidase inhibitor antidepressant drug tranylcypromine and the typical antipsychotic drug trifluoperazine that has been used in the treatment of major depressive disorder .[1] [2] [3] It contains 10 mg tranylcypromine and 1 mg trifluoperazine.[3] [4] The drug has been in clinical use since at least 1961.[3]
It may come to assume a certain place in the treatment of borderline personality disorder .[5]
See also
References
^ Dart RC (2004). "Monoamine Oxidase Inhibitors" . Medical Toxicology . Lippincott Williams & Wilkins. pp. 825–. ISBN 978-0-7817-2845-4 .
^ Stahl SM (15 May 2014). Prescriber's Guide: Stahl's Essential Psychopharmacology . Cambridge University Press. pp. 783–. ISBN 978-1-107-67502-5 .
^ a b c Straker M, Grauer H (July 1961). "Clinical Study of a Potent Antidepressant, Tranylcypromine with Trifluorperazine (Parstelin ), in the Aged Chronically Ill" . Canadian Medical Association Journal . 85 (3): 127–130. PMC 1848140 . PMID 20326829 .
^ Kalinowsky LB, Hippius H, Klein HE (1982). Biological Treatments in Psychiatry . Grune and Stratton, Harcourt Brace Jovanovich. ISBN 978-0-8089-1423-5 .
^ Cowdry, R. W., & Gardner, D. L. (1988). Pharmacotherapy of borderline personality disorder. Alprazolam, carbamazepine, trifluoperazine, and tranylcypromine. Archives of general psychiatry, 45(2), 111–119. https://doi.org/10.1001/archpsyc.1988.01800260015002
SSRIs Tooltip Selective serotonin reuptake inhibitors SNRIs Tooltip Serotonin–norepinephrine reuptake inhibitors NRIs Tooltip Norepinephrine reuptake inhibitors NDRIs Tooltip Norepinephrine–dopamine reuptake inhibitors NaSSAs Tooltip Noradrenergic and specific serotonergic antidepressants SARIs Tooltip Serotonin antagonist and reuptake inhibitors SMS Tooltip Serotonin modulator and stimulators Others
TCAs Tooltip Tricyclic antidepressants TeCAs Tooltip Tetracyclic antidepressants Others
Non-selective MAOA Tooltip Monoamine oxidase A -selectiveMAOB Tooltip Monoamine oxidase B -selective
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