Fluanisone

Fluanisone
Clinical data
ATC code	N05AD09 (WHO) ;
Identifiers
	IUPAC name 1-(4-Fluorophenyl)-4-butan-1-one;
CAS Number	1480-19-9;
PubChem CID	15139;
DrugBank	DB13665 ;
ChemSpider	14410 ;
UNII	1D0W98U1I4;
KEGG	D02621 ;
ChEMBL	ChEMBL58792 ;
CompTox Dashboard (EPA)	DTXSID4045711 ;
ECHA InfoCard	100.014.581
Chemical and physical data
Formula	C21H25FN2O2
Molar mass	356.441 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES Fc1ccc(cc1)C(=O)CCCN3CCN(c2ccccc2OC)CC3;
	InChI InChI=1S/C21H25FN2O2/c1-26-21-7-3-2-5-19(21)24-15-13-23(14-16-24)12-4-6-20(25)17-8-10-18(22)11-9-17/h2-3,5,7-11H,4,6,12-16H2,1H3 ; Key:IRYFCWPNDIUQOW-UHFFFAOYSA-N ;
	(verify)

Fluanisone is a typical antipsychotic and sedative of the butyrophenone chemical class.^[1] It is used in the treatment of schizophrenia and mania. It is also a component (along with fentanyl) of the injectable veterinary formulation fentanyl/fluanisone (Hypnorm)^[2] where it is used for rodent analgesia during short surgical procedures.

References

^ Janssen PA (1967). "Haloperidol and related butyrophenones". In Gordon M (ed.). Psychopharmacological agents. Medicinal Chemistry. Vol. 2. New York: Academic Press. pp. 199–248 (227). ISBN 978-1-4832-7446-1.
^ "Fluanisone". drugs.com.

[1] Janssen PA (1967). "Haloperidol and related butyrophenones". In Gordon M (ed.). Psychopharmacological agents. Medicinal Chemistry. Vol. 2. New York: Academic Press. pp. 199–248 (227). ISBN 978-1-4832-7446-1.

[2] "Fluanisone". drugs.com.

[1]

[2]

v t e Antipsychotics (N05A)
Typical	Butyrophenones: Benperidol Bromperidol Bromperidol decanoate Droperidol Haloperidol^# Haloperidol decanoate Moperone Pipamperone Spiperone Timiperone Trifluperidol Diphenylbutylpiperidines: Fluspirilene Penfluridol Pimozide Phenothiazines: Acepromazine Acetophenazine Butaperazine Carphenazine (carfenazine)^‡ Chlorpromazine Cyamemazine Dixyrazine Fluphenazine Fluphenazine decanoate Fluphenazine enanthate Levomepromazine (methotrimeprazine) Mesoridazine Perazine Periciazine Perphenazine BL-1020 Perphenazine decanoate Perphenazine enanthate Piperacetazine Pipotiazine Pipotiazine palmitate Pipotiazine undecylenate Prochlorperazine Promazine Sulforidazine Thiopropazate Thioproperazine Thioridazine Trifluoperazine Triflupromazine Thioxanthenes: Chlorprothixene Clopenthixol Clopenthixol decanoate Flupentixol Flupentixol decanoate Tiotixene (thiothixene) Zuclopenthixol Zuclopenthixol acetate Zuclopenthixol decanoate
Disputed	Benzamides: Amisulpride Levosulpiride Nemonapride Remoxipride^‡ Sulpiride Sultopride Tiapride Veralipride^‡ Butyrophenones: Melperone Tricyclics: Carpipramine Clocapramine Clorotepine Clotiapine Loxapine Mosapramine Oxyprothepin decanoate Others: Molindone
Atypical	Benzisoxazole/benzisothiazoles: Iloperidone Lurasidone Paliperidone Paliperidone palmitate Perospirone Risperidone^# Ziprasidone Butyrophenones: Lumateperone Phenylpiperazines/quinolinones: Aripiprazole Aripiprazole lauroxil Brilaroxazine^† Brexpiprazole Cariprazine Tricyclics: Asenapine Clozapine^# Olanzapine (+samidorphan) Quetiapine Zotepine Others: Blonanserin Pimavanserin Sertindole
Others	Monoamine-depleting agents: Oxypertine Reserpine Tetrabenazine Others/unknown: Azacyclonol
^#WHO-EM ^‡Withdrawn from market Clinical trials: ^†Phase III ^§Never to phase III

Clinical data

ATC code	N05AD09 (WHO)
Identifiers
IUPAC name 1-(4-Fluorophenyl)-4-butan-1-one
CAS Number	1480-19-9
PubChem CID	15139
DrugBank	DB13665^Y
ChemSpider	14410^Y
UNII	1D0W98U1I4
KEGG	D02621^Y
ChEMBL	ChEMBL58792^Y
CompTox Dashboard (EPA)	DTXSID4045711
ECHA InfoCard	100.014.581
Chemical and physical data
Formula	C₂₁H₂₅FN₂O₂
Molar mass	356.441 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES Fc1ccc(cc1)C(=O)CCCN3CCN(c2ccccc2OC)CC3
InChI InChI=1S/C21H25FN2O2/c1-26-21-7-3-2-5-19(21)24-15-13-23(14-16-24)12-4-6-20(25)17-8-10-18(22)11-9-17/h2-3,5,7-11H,4,6,12-16H2,1H3^Y Key:IRYFCWPNDIUQOW-UHFFFAOYSA-N^Y
(verify)

See also

References