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Names | |
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Preferred IUPAC name
N-(6,11-Dihydrodibenzothiepin-11-yl)-4-butanamide | |
Identifiers | |
3D model (JSmol)
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ChemSpider |
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KEGG |
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PubChem CID
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UNII | |
CompTox Dashboard (EPA)
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Properties | |
C28H30FN3OS | |
Molar mass | 475.63 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C , 100 kPa).
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Monatepil is a calcium channel blocker and α1-adrenergic receptor antagonist used as an antihypertensive.[1]
References
- ^ Sugimoto T, Hosoki K, Karasawa T (July 1995). "Relative contribution of alpha 1-adrenoceptor blocking activity to the hypotensive effect of the novel calcium antagonist monatepil". Journal of Cardiovascular Pharmacology. 26 (1): 55–60. doi:10.1097/00005344-199507000-00009. PMID 7564365. S2CID 1548014.
Sympatholytics (antagonize α-adrenergic vasoconstriction) | |||||
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Other antagonists |
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Calcium |
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Potassium |
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Sodium |
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Chloride |
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Others |
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α1 |
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α2 |
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β |
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