Elopiprazole

Elopiprazole
Clinical data
Routes of; administration	Oral
ATC code	none;
Legal status
Legal status	In general: uncontrolled;
Identifiers
	IUPAC name 1-(1-benzofuran-7-yl)-4-5-(4-fluorophenyl)-1H-pyrrol-2-ylmethylpiperazine;
CAS Number	115464-77-2;
PubChem CID	208917;
ChemSpider	181013;
UNII	419A0R564U;
ChEMBL	ChEMBL292187;
CompTox Dashboard (EPA)	DTXSID20151109 ;
Chemical and physical data
Formula	C23H22FN3O
Molar mass	375.447 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES Fc1ccc(cc1)c2ccc(nH2)CN5CCN(c4cccc3c4occ3)CC5;

Elopiprazole is an antipsychotic drug of the phenylpiperazine class which was never marketed.^[1]

Referencesedit

^ van Wijngaarden I, Kruse CG, van Hes R, van der Heyden JA, Tulp MT (November 1987). "2-Phenylpyrroles as conformationally restricted benzamide analogues. A new class of potential antipsychotics. 1". Journal of Medicinal Chemistry. 30 (11): 2099–104. doi:10.1021/jm00394a028. PMID 2889830.

[pmid2889830-1] van Wijngaarden I, Kruse CG, van Hes R, van der Heyden JA, Tulp MT (November 1987). "2-Phenylpyrroles as conformationally restricted benzamide analogues. A new class of potential antipsychotics. 1". Journal of Medicinal Chemistry. 30 (11): 2099–104. doi:10.1021/jm00394a028. PMID 2889830.

[1]

v t e Antipsychotics (N05A)
Typical	Butyrophenones: Benperidol Bromperidol Bromperidol decanoate Droperidol Haloperidol^# Haloperidol decanoate Moperone Pipamperone Spiperone Timiperone Trifluperidol Diphenylbutylpiperidines: Fluspirilene Penfluridol Pimozide Phenothiazines: Acepromazine Acetophenazine Butaperazine Carphenazine (carfenazine)^‡ Chlorpromazine Cyamemazine Dixyrazine Fluphenazine Fluphenazine decanoate Fluphenazine enanthate Levomepromazine (methotrimeprazine) Mesoridazine Perazine Periciazine Perphenazine BL-1020 Perphenazine decanoate Perphenazine enanthate Piperacetazine Pipotiazine Pipotiazine palmitate Pipotiazine undecylenate Prochlorperazine Promazine Sulforidazine Thiopropazate Thioproperazine Thioridazine Trifluoperazine Triflupromazine Thioxanthenes: Chlorprothixene Clopenthixol Clopenthixol decanoate Flupentixol Flupentixol decanoate Tiotixene (thiothixene) Zuclopenthixol Zuclopenthixol acetate Zuclopenthixol decanoate
Disputed	Benzamides: Amisulpride Levosulpiride Nemonapride Remoxipride^‡ Sulpiride Sultopride Tiapride Veralipride^‡ Butyrophenones: Melperone Tricyclics: Carpipramine Clocapramine Clorotepine Clotiapine Loxapine Mosapramine Oxyprothepin decanoate Others: Molindone
Atypical	Benzisoxazole/benzisothiazoles: Iloperidone Lurasidone Paliperidone Paliperidone palmitate Perospirone Risperidone^# Ziprasidone Butyrophenones: Lumateperone Phenylpiperazines/quinolinones: Aripiprazole Aripiprazole lauroxil Brilaroxazine^† Brexpiprazole Cariprazine Tricyclics: Asenapine Clozapine^# Olanzapine (+samidorphan) Quetiapine Zotepine Others: Blonanserin Pimavanserin Sertindole
Others	Monoamine-depleting agents: Oxypertine Reserpine Tetrabenazine Others/unknown: Azacyclonol
^#WHO-EM ^‡Withdrawn from market Clinical trials: ^†Phase III ^§Never to phase III

Clinical data


Routes of administration	Oral
ATC code	none
Legal status
Legal status	In general: uncontrolled
Identifiers
IUPAC name 1-(1-benzofuran-7-yl)-4-5-(4-fluorophenyl)-1H-pyrrol-2-ylmethylpiperazine
CAS Number	115464-77-2
PubChem CID	208917
ChemSpider	181013
UNII	419A0R564U
ChEMBL	ChEMBL292187
CompTox Dashboard (EPA)	DTXSID20151109
Chemical and physical data
Formula	C₂₃H₂₂FN₃O
Molar mass	375.447 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES Fc1ccc(cc1)c2ccc(nH2)CN5CCN(c4cccc3c4occ3)CC5

See alsoedit

Referencesedit