T-1152

T-1152
Names
	Other names TL-1178; Stedman's meta compound;
Identifiers
CAS Number	3983-39-9 ;
3D model (JSmol)	Interactive image;
ChemSpider	18732;
PubChem CID	19886;
CompTox Dashboard (EPA)	DTXSID60960393;
	InChI InChI=1S/C11H16N2O2.HI/c1-12-11(14)15-10-7-5-6-9(8-10)13(2,3)4;/h5-8H,1-4H3;1H Key: MIAARRZWMRMHIS-UHFFFAOYSA-N;
	SMILES CNC(=O)OC1=CC=CC(=C1)(C)(C)C.;
Hazards
	Lethal dose or concentration (LD, LC):
LD50 (median dose)	270 μg/kg (subcutaneous, mice); 115 μg/kg (intravenous, mice); 260 μg/kg (subcutaneous, rabbits)
LDLo (lowest published)	2.5 mg/kg (oral, mice)
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C , 100 kPa). Infobox references

T-1152 is a quaternary carbamate anticholinesterase. It is synthesized by reaction of m-dimethylaminophenol with methyl isocyanate, followed by quaternization with methyl iodide.^[3] Since T-1152 is toxic by ingestion, it was patented as a rodenticide in 1932.^[2]

The chloride and methylsulfate salt of T-1152 is T-1690 (TL-1226) and AR-13, respectively.^[1]

References

^ ^a ^b ^c ^d Chemical Warfare Agents, and Related Chemical Problems. Parts I-II.
^ ^a ^b "Product for destroying animals".
^ Stedman, Edgar (1 January 1926). "Studies on the Relationship between Chemical Constitution and Physiological Action". Biochemical Journal. 20 (4): 719–734. doi:10.1042/bj0200719. PMC 1251776. PMID 16743713.

Zdroj:https://en.wikipedia.org?pojem=T-1152
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[PB158508-1] Chemical Warfare Agents, and Related Chemical Problems. Parts I-II.

[pat-2] "Product for destroying animals".

[3] Stedman, Edgar (1 January 1926). "Studies on the Relationship between Chemical Constitution and Physiological Action". Biochemical Journal. 20 (4): 719–734. doi:10.1042/bj0200719. PMC 1251776. PMID 16743713.

[1]

[2]

[3]

Names

Other names TL-1178 Stedman's meta compound
Identifiers
CAS Number	3983-39-9^Y
3D model (JSmol)	Interactive image
ChemSpider	18732
PubChem CID	19886
CompTox Dashboard (EPA)	DTXSID60960393
InChI InChI=1S/C11H16N2O2.HI/c1-12-11(14)15-10-7-5-6-9(8-10)13(2,3)4;/h5-8H,1-4H3;1H Key: MIAARRZWMRMHIS-UHFFFAOYSA-N
SMILES CNC(=O)OC1=CC=CC(=C1)(C)(C)C.
Hazards
Lethal dose or concentration (LD, LC):
LD₅₀ (median dose)	270 μg/kg (subcutaneous, mice)^[1] 115 μg/kg (intravenous, mice)^[1] 260 μg/kg (subcutaneous, rabbits)^[1]
LD_Lo (lowest published)	2.5 mg/kg (oral, mice)^[2]
Except where otherwise noted, data are given for materials in their standard state (at 25 °C , 100 kPa). Infobox references

See also

References