Drug-induced pruritus

Drug-induced pruritus
Drug-induced pruritus
Specialty	Dermatology

Drug-induced pruritus is itchiness of the skin caused by medication, a pruritic reaction that is generalized.^[1]^: 57

Signs and symptoms

Depending on the causing agent, symptoms may start out acutely, go away when the drug is stopped, or develop into a chronic pruritus that lasts longer than six weeks.^[2]

Causes

A common anti-malarial medication called chloroquine may cause pruritus for unknown reasons. Other antimalarials like amodiaquine, halofantrine, and hydroxychloroquine have also been linked to pruritus, albeit less frequently and to a lesser extent.^[2]

Another class of medications known to occasionally cause itching is known as serotonin reuptake inhibitors.^[3]

Itching is one of the most frequent adverse effects of opioid therapy.^[4]

A common artificial colloid used in clinical fluid management is hydroxyethyl starch (HES). Well-defined side effects, such as coagulopathy, clinical bleeding, anaphylactoid reactions, and pruritus, can make using HES more difficult.^[5]

Epidemiology

Thirty-three percent of the 3,671 cases of cutaneous adverse drug reactions included itching as a common complaint.^[6]

References

^ James WD, Berger T, Elston D (2006). Andrews' Diseases of the Skin: Clinical Dermatology (10th ed.). Philadelphia: Saunders Elsevier. ISBN 978-0-7216-2921-6.
^ ^a ^b Reich, A; Ständer, S; Szepietowski, JC (2009). "Drug-induced Pruritus: A Review". Acta Dermato Venereologica. 89 (3). Medical Journals Sweden AB: 236–244. doi:10.2340/00015555-0650. ISSN 0001-5555. PMID 19479118.
^ Cederberg, Jonas; Knight, Stefan; Svenson, Svante; Melhus, Håkan (2004). "Itch and skin rash from chocolate during fluoxetine and sertraline treatment: Case report". BMC Psychiatry. 4 (1). doi:10.1186/1471-244X-4-36. ISSN 1471-244X. PMC 533866. PMID 15522120.
^ Katcher, Jerald; Walsh, Declan (1999). "Opioid-Induced Itching". Journal of Pain and Symptom Management. 17 (1). Elsevier BV: 70–72. doi:10.1016/s0885-3924(98)00115-8. ISSN 0885-3924. PMID 9919868.
^ Bork, K. (2005). "Pruritus precipitated by hydroxyethyl starch: a review". British Journal of Dermatology. 152 (1). Oxford University Press (OUP): 3–12. doi:10.1111/j.1365-2133.2004.06272.x. ISSN 0007-0963. PMID 15656795. S2CID 13483776.
^ Patel, TejasK; Thakkar, SejalH; Sharma, DC (2014). "Cutaneous adverse drug reactions in Indian population: A systematic review". Indian Dermatology Online Journal. 5 (6). Medknow: S76-86. doi:10.4103/2229-5178.146165. ISSN 2229-5178. PMC 4290186. PMID 25593813.

External links

DermNet

Zdroj:https://en.wikipedia.org?pojem=Drug-induced_pruritus
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[Andrews-1] James WD, Berger T, Elston D (2006). Andrews' Diseases of the Skin: Clinical Dermatology (10th ed.). Philadelphia: Saunders Elsevier. ISBN 978-0-7216-2921-6.

[Reich_Ständer_Szepietowski_2009_pp._236–244-2] Reich, A; Ständer, S; Szepietowski, JC (2009). "Drug-induced Pruritus: A Review". Acta Dermato Venereologica. 89 (3). Medical Journals Sweden AB: 236–244. doi:10.2340/00015555-0650. ISSN 0001-5555. PMID 19479118.

[Cederberg_Knight_Svenson_Melhus_2004_p.-3] Cederberg, Jonas; Knight, Stefan; Svenson, Svante; Melhus, Håkan (2004). "Itch and skin rash from chocolate during fluoxetine and sertraline treatment: Case report". BMC Psychiatry. 4 (1). doi:10.1186/1471-244X-4-36. ISSN 1471-244X. PMC 533866. PMID 15522120.

[Katcher_Walsh_1999_pp._70–72-4] Katcher, Jerald; Walsh, Declan (1999). "Opioid-Induced Itching". Journal of Pain and Symptom Management. 17 (1). Elsevier BV: 70–72. doi:10.1016/s0885-3924(98)00115-8. ISSN 0885-3924. PMID 9919868.

[Bork_2005_pp._3–12-5] Bork, K. (2005). "Pruritus precipitated by hydroxyethyl starch: a review". British Journal of Dermatology. 152 (1). Oxford University Press (OUP): 3–12. doi:10.1111/j.1365-2133.2004.06272.x. ISSN 0007-0963. PMID 15656795. S2CID 13483776.

[Patel_Thakkar_Sharma_2014_p._76-6] Patel, TejasK; Thakkar, SejalH; Sharma, DC (2014). "Cutaneous adverse drug reactions in Indian population: A systematic review". Indian Dermatology Online Journal. 5 (6). Medknow: S76-86. doi:10.4103/2229-5178.146165. ISSN 2229-5178. PMC 4290186. PMID 25593813.

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[6]

Classification	D ICD-11: EC90.2 ICD-10: L29.8 SNOMED CT: 724843002
External resources	Scholia: Q5308818

v t e Dermatitis and eczema
Atopic dermatitis	Prurigo gestationis Sweat allergy
Seborrheic dermatitis	Pityriasis simplex capillitii Cradle cap
Contact dermatitis (allergic, irritant)	plants: Urushiol-induced contact dermatitis African blackwood dermatitis Tulip fingers other: Abietic acid dermatitis Diaper rash Airbag dermatitis Baboon syndrome Contact stomatitis Metal allergy Protein contact dermatitis
Eczema	Autoimmune estrogen dermatitis Autoimmune progesterone dermatitis Breast eczema Ear eczema Eyelid dermatitis Topical steroid withdrawal Hand eczema Chronic vesiculobullous hand eczema Hyperkeratotic hand dermatitis Autosensitization dermatitis/Id reaction Candidid Dermatophytid Molluscum dermatitis Circumostomy eczema Dyshidrosis Juvenile plantar dermatosis Nummular eczema Nutritional deficiency eczema Sulzberger–Garbe syndrome Xerotic eczema
Pruritus/Itch/ Prurigo	Lichen simplex chronicus/Prurigo nodularis by location: Pruritus ani Pruritus scroti Pruritus vulvae Scalp pruritus Drug-induced pruritus Hydroxyethyl starch-induced pruritus Senile pruritus Aquagenic pruritus Aquadynia Adult blaschkitis due to liver disease Biliary pruritus Cholestatic pruritus Prion pruritus Prurigo pigmentosa Prurigo simplex Puncta pruritica Uremic pruritus
Other	substances taken internally: Bromoderma Fixed drug reaction Nummular dermatitis Pityriasis alba Papuloerythroderma of Ofuji

Signs and symptoms

Causes

Epidemiology

See also

References

External links