Hydroxyethyl starch-induced pruritus

Hydroxyethyl starch-induced pruritus
Hydroxyethyl starch-induced pruritus
	Structure of Hydroxyethyl starch.
Specialty	Dermatology

Hydroxyethyl starch-induced pruritus is an intense itching, lasting for as long as one year, occurring following hydroxyethyl starch intravenous infusion for vascular insufficiency.^[1]^[2]^: 401There is no treatment for the itch.

An updated clinical review on storage in different tissues describes a pattern of storage in the reticuloendothelial system and also the skin (Wiedermann). Differential storage described via immuno-electron microscopy, see Ständer 2001 below.

References

^ Bork K (January 2005). "Pruritus precipitated by hydroxyethyl starch: a review". The British Journal of Dermatology. 152 (1): 3–12. doi:10.1111/j.1365-2133.2004.06272.x. PMID 15656795.
^ Fitzpatrick TB, Freedberg IM, Eisen AZ, Goldsmith LA, Austen KF, Wolff K (2003). Fitzpatrick's Dermatology in General Medicine (6th ed.). McGraw-Hill, Medical Pub. Division. ISBN 978-0-07-138076-8.

Wiedermann CJ, Joannidis M (February 2014). "Accumulation of hydroxyethyl starch in human and animal tissues: a systematic review". Intensive Care Medicine. 40 (2): 160–170. doi:10.1007/s00134-013-3156-9. PMC 7728635. PMID 24257970.
Ständer S, Szépfalusi Z, Bohle B, Ständer H, Kraft D, Luger TA, Metze D (May 2001). "Differential storage of hydroxyethyl starch (HES) in the skin: an immunoelectron-microscopical long-term study". Cell and Tissue Research. 304 (2): 261–269. doi:10.1007/s004410000324. PMID 11396719.

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[1] Bork K (January 2005). "Pruritus precipitated by hydroxyethyl starch: a review". The British Journal of Dermatology. 152 (1): 3–12. doi:10.1111/j.1365-2133.2004.06272.x. PMID 15656795.

[Fitz2-2] Fitzpatrick TB, Freedberg IM, Eisen AZ, Goldsmith LA, Austen KF, Wolff K (2003). Fitzpatrick's Dermatology in General Medicine (6th ed.). McGraw-Hill, Medical Pub. Division. ISBN 978-0-07-138076-8.

[1]

[2]

See also

References

Further reading