Cetrimide

Cetrimide
Identifiers
	Compounds; Cetrimide: Mixture of; C12: Dodecyltrimethylammonium bromide; C14: Tetradecyltrimethylammonium bromide; C16: Hexadecyltrimethylammonium bromide;
CAS Number	Cetrimide: 8044-71-1; C12: 1119-97-7; C14: 57-09-0; C16: 1119-94-4;
ECHA InfoCard	100.118.908
EC Number	Cetrimide: 617-073-5;
PubChem CID	C12: 14250; C14: 5974; C16: 14249;
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C , 100 kPa). Infobox references

Cetrimide, or alkyltrimethylammonium bromide, is an antiseptic which is a mixture of three quaternary ammonium compounds: tetradonium bromide (TTAB or MITMAB), cetrimonium bromide (CTAB), and laurtrimonium bromide (DTAB or LTAB).^[1] It was first discovered and developed by ICI and introduced under the brand name Cetavlon.^[2] It is used as a 1-3 % solution for cleaning roadside accident wounds.^[3] ICI also introduced Savlon, which was a combination of cetrimide and chlorhexidine. ICI later sold the Savlon brand OTC to Johnson & Johnson in May 1992.^[4] Cetrimide is used in various applications such as antiseptic agents, diagnostic test and analysis, topical formulations, and dental treatment.^[5]

References

^ Council of Europe (2007). European Pharmacopoeia (Ph. Eur.) (6.0 ed.). Strasbourg: The Stationery Office. pp. 1484–5. ISBN 978-92-871-6054-6. OCLC 170932841.
^ "Newspaper Article - Page 11 Advertisements Column 1". Archived from the original on 2013-10-05. Retrieved 2013-08-15.
^ Tripathi, KD. Essentials of Medical Pharmacology (7th ed.). p. 900.
^ "JOHNSON & JOHNSON ACQUIRES SAVLON OTC BRANDS FROM ICI - Free Online Library". Archived from the original on 2013-10-05.
^ "Cetrimide Applications". 22 October 2021. Archived from the original on 2019-04-05.

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[European_pharmacopoeia_2007_p._1484–5-1] Council of Europe (2007). European Pharmacopoeia (Ph. Eur.) (6.0 ed.). Strasbourg: The Stationery Office. pp. 1484–5. ISBN 978-92-871-6054-6. OCLC 170932841.

[2] "Newspaper Article - Page 11 Advertisements Column 1". Archived from the original on 2013-10-05. Retrieved 2013-08-15.

[3] Tripathi, KD. Essentials of Medical Pharmacology (7th ed.). p. 900.

[4] "JOHNSON & JOHNSON ACQUIRES SAVLON OTC BRANDS FROM ICI - Free Online Library". Archived from the original on 2013-10-05.

[5] "Cetrimide Applications". 22 October 2021. Archived from the original on 2019-04-05.

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v t e Antiseptics and disinfectants (D08)
Acridine derivatives	Ethacridine lactate 9-Aminoacridine Euflavine
Biguanides and amidines	Dibrompropamidine Chlorhexidine^# Propamidine Hexamidine Polihexanide
Phenol and derivatives	Hexachlorophene Policresulen Phenol Triclosan Triclocarban Chloroxylenol^# Biphenylol Fenticlor
Nitrofuran derivatives	Nitrofurazone
Iodine products	Iodine/octylphenoxypolyglycolether Povidone-iodine^# Diiodohydroxypropane
Quinoline derivatives	Dequalinium Chlorquinaldol Oxyquinoline Clioquinol
Quaternary ammonium compounds	Benzalkonium Benzethonium chloride Cetrimonium (bromide/chloride) Cetylpyridinium Cetrimide Benzoxonium chloride Didecyldimethylammonium chloride
Mercurial products	Mercuric amidochloride Phenylmercuric borate Mercuric chloride Merbromin Nitromersol Thiomersal Mercuric iodide
Silver compounds	Silver nitrate
Alcohols	Propanol (propyl alcohol) Isopropanol (isopropyl alcohol) Ethanol (ethyl alcohol)^#
Other	Potassium permanganate Sodium hypochlorite Halazone Monalazone Hydrogen peroxide Eosin Chloramine-T (tosylchloramide) Octenidine dihydrochloride
^#WHO-EM ^‡Withdrawn from market Clinical trials: ^†Phase III ^§Never to phase III

v t e Other dermatological preparations (D11)
Anti-seborrheics	Antiandrogens Bicalutamide Cyproterone acetate Flutamide Spironolactone Antifungals Bifonazole Cetrimonium bromide (cetrimide) Ciclopirox olamine (ciclopirox) Climbazole Clotrimazole Ketoconazole Miconazole Piroctone olamine Selenium disulfide (selenium sulfide) Xenysalate Zinc pyrithione (pyrithione zinc) Antihistamines Calcineurin inhibitors Cyclosporin Pimecrolimus Tacrolimus Isotretinoin Keratolytics Coal tar Resorcinol Salicylic acid Sulfur Urea (urea-containing cream) Lithium salts Lithium gluconate Lithium succinate Topical corticosteroids (e.g., hydrocortisone)
Skin lightening	Hydroquinone Mequinol Monobenzone
Skin darkening	Afamelanotide Melanotan II
Anti-inflammatories	Oxaceprol Gamolenic acid Pimecrolimus Tacrolimus Alitretinoin Topical corticosteroids (e.g., hydrocortisone)
Alopecia treatments	5α-Reductase inhibitors Alfatradiol Dutasteride Finasteride Saw palmetto extract Antiandrogens Bicalutamide Cyproterone acetate Flutamide Spironolactone Topilutamide (fluridil) Potassium channel openers Minoxidil Others Nepidermin Ritlecitinib
Hair growth inhibitors	5α-Reductase inhibitors Dutasteride Finasteride Antiandrogens Bicalutamide Cyproterone acetate Flutamide Spironolactone Eflornithine
Others	Abrocitinib Aminobenzoate potassium Androgens (e.g., testosterone) Brimonidine Caffeine Calcium gluconate Collagen Crisaborole Cromoglicic acid Deoxycholic acid Diclofenac Dupilumab Estrogens (e.g., estradiol) Glycopyrronium tosylate Hyaluronic acid Hydrogen peroxide Ivermectin Magnesium sulfate Metandienone Oxymetazoline Pregnenolone acetate Progestogens (e.g., progesterone) Povidone-iodine Tiratricol Tralokinumab

Identifiers

Compounds Cetrimide: Mixture of C₁₂: Dodecyltrimethylammonium bromide C₁₄: Tetradecyltrimethylammonium bromide C₁₆: Hexadecyltrimethylammonium bromide
CAS Number	Cetrimide: 8044-71-1 C₁₂: 1119-97-7 C₁₄: 57-09-0 C₁₆: 1119-94-4
ECHA InfoCard	100.118.908
EC Number	Cetrimide: 617-073-5
PubChem CID	C₁₂: 14250 C₁₄: 5974 C₁₆: 14249
Except where otherwise noted, data are given for materials in their standard state (at 25 °C , 100 kPa). Infobox references