GPR135

GPR135
Identifiers
Aliases	GPR135, HUMNPIIY20, G protein-coupled receptor 135
External IDs	OMIM: 607970; MGI: 2676315; HomoloGene: 11211; GeneCards: GPR135; OMA:GPR135 - orthologs
Gene location (Human)
Chr.	Chromosome 14 (human)
End	59,465,380 bp
Gene location (Mouse)
Chr.	Chromosome 12 (mouse)
End	72,117,899 bp
RNA expression pattern
	Top expressed in
	left testis; ; right testis; ; sperm; ; testicle; ; right uterine tube; ; buccal mucosa cell; ; right coronary artery; ; ventricular zone; ; left coronary artery; ; popliteal artery;
	Top expressed in
	substantia nigra; ; Region I of hippocampus proper; ; ventromedial nucleus; ; paraventricular nucleus of hypothalamus; ; dorsomedial hypothalamic nucleus; ; arcuate nucleus; ; lateral hypothalamus; ; fossa; ; subiculum; ; cingulate gyrus;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	G protein-coupled receptor activity; signal transducer activity; protein binding; arrestin family protein binding;
Cellular component	integral component of membrane; membrane; plasma membrane; endosome; endosome membrane;
Biological process	G protein-coupled receptor signaling pathway; signal transduction;
	Sources:Amigo / QuickGO
Orthologs
	64582
	238252
	ENSG00000181619
	ENSMUSG00000043398
	Q8IZ08
	Q7TQP2
	NM_022571
	NM_181752
	NP_072093
	NP_861417
	Wikidata
View/Edit Human	View/Edit Mouse

Probable G-protein coupled receptor 135 is a protein that in humans is encoded by the GPR135 gene.^[5]^[6]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000181619 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000043398 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Fredriksson R, Hoglund PJ, Gloriam DE, Lagerstrom MC, Schioth HB (Nov 2003). "Seven evolutionarily conserved human rhodopsin G protein-coupled receptors lacking close relatives". FEBS Lett. 554 (3): 381–8. doi:10.1016/S0014-5793(03)01196-7. PMID 14623098. S2CID 11563502.
^ "Entrez Gene: GPR135 G protein-coupled receptor 135".

Kunz D, Gerard NP, Gerard C (1992). "The human leukocyte platelet-activating factor receptor. cDNA cloning, cell surface expression, and construction of a novel epitope-bearing analog". J. Biol. Chem. 267 (13): 9101–6. doi:10.1016/S0021-9258(19)50394-5. PMID 1374385.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Vassilatis DK, Hohmann JG, Zeng H, et al. (2003). "The G protein-coupled receptor repertoires of human and mouse". Proc. Natl. Acad. Sci. U.S.A. 100 (8): 4903–8. Bibcode:2003PNAS..100.4903V. doi:10.1073/pnas.0230374100. PMC 153653. PMID 12679517.
Vanti WB, Nguyen T, Cheng R, et al. (2003). "Novel human G-protein-coupled receptors". Biochem. Biophys. Res. Commun. 305 (1): 67–71. doi:10.1016/S0006-291X(03)00709-5. PMID 12732197.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.

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[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000181619 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000043398 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid14623098-5] Fredriksson R, Hoglund PJ, Gloriam DE, Lagerstrom MC, Schioth HB (Nov 2003). "Seven evolutionarily conserved human rhodopsin G protein-coupled receptors lacking close relatives". FEBS Lett. 554 (3): 381–8. doi:10.1016/S0014-5793(03)01196-7. PMID 14623098. S2CID 11563502.

[entrez-6] "Entrez Gene: GPR135 G protein-coupled receptor 135".

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References

Further reading