Trimedoxime bromide

Trimedoxime bromide
Clinical data
Routes of; administration	Intramuscular injection
ATC code	None;
Legal status
Legal status	Experimental; in military use;
Pharmacokinetic data
Elimination half-life	2 hours (mean)
Identifiers
	IUPAC name 1,1′-propane-1,3-diylbis{4-pyridinium} dibromide;
CAS Number	56-97-3;
PubChem CID	5359236;
ChemSpider	4514238;
UNII	ED0GXI9825;
CompTox Dashboard (EPA)	DTXSID101036063 ;
ECHA InfoCard	100.000.276
Chemical and physical data
Formula	C15H18Br2N4O2
Molar mass	446.143 g·mol−1

Trimedoxime bromide (INN), also known as dipyroxime or TMB-4, is an oxime used in the treatment of organophosphate poisoning^[1] It is chemically related to asoxime, pralidoxime, and obidoxime.^[2]

References

^ Dhuguru J, Zviagin E, Skouta R (January 2022). "FDA-Approved Oximes and Their Significance in Medicinal Chemistry". Pharmaceuticals. 15 (1). Basel, Switzerland: 66. doi:10.3390/ph15010066. PMC 8779982. PMID 35056123.
^ Gupta R, Parmar M (2022). "Pralidoxime". StatPearls. Treasure Island (FL): StatPearls Publishing. PMID 32644334.

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[Dhuguru_2022-1] Dhuguru J, Zviagin E, Skouta R (January 2022). "FDA-Approved Oximes and Their Significance in Medicinal Chemistry". Pharmaceuticals. 15 (1). Basel, Switzerland: 66. doi:10.3390/ph15010066. PMC 8779982. PMID 35056123.

[2] Gupta R, Parmar M (2022). "Pralidoxime". StatPearls. Treasure Island (FL): StatPearls Publishing. PMID 32644334.

[1]

[2]

Clinical data

Routes of administration	Intramuscular injection
ATC code	None
Legal status
Legal status	Experimental; in military use
Pharmacokinetic data
Elimination half-life	2 hours (mean)
Identifiers
IUPAC name 1,1′-propane-1,3-diylbis{4-pyridinium} dibromide
CAS Number	56-97-3
PubChem CID	5359236
ChemSpider	4514238
UNII	ED0GXI9825
CompTox Dashboard (EPA)	DTXSID101036063
ECHA InfoCard	100.000.276
Chemical and physical data
Formula	C₁₅H₁₈Br₂N₄O₂
Molar mass	446.143 g·mol⁻¹