Dimemebfe

Dimemebfe
Clinical data
Other names	5-MeO-BFE
Legal status
Legal status	DE: NpSG (Industrial and scientific use only); UK: Class A; US: Unscheduled and not FDA approved;
Identifiers
	IUPAC name 2-(5-Methoxy-1-benzofuran-3-yl)-N,N-dimethylethanamine;
CAS Number	140853-58-3 ;
PubChem CID	126589;
ChemSpider	112474 ;
UNII	9JXZ3RM7Y9;
CompTox Dashboard (EPA)	DTXSID80161481 ;
Chemical and physical data
Formula	C13H17NO2
Molar mass	219.284 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CN(C)CCc1coc(c1c2)ccc2OC;
	InChI InChI=1S/C13H17NO2/c1-14(2)7-6-10-9-16-13-5-4-11(15-3)8-12(10)13/h4-5,8-9H,6-7H2,1-3H3 ; Key:WBPQJTBOQCCTFX-UHFFFAOYSA-N ;
	(what is this?) (verify)

Dimemebfe (5-MeO-BFE) is a recreational drug^[1] and research chemical. It acts as an agonist for the 5-HT_1A and 5-HT₂ family of serotonin receptors. It is related in structure to the psychedelic tryptamine derivative 5-MeO-DMT, but with the indole nitrogen replaced by oxygen, making dimemebfe a benzofuran derivative. It is several times less potent as a serotonin agonist than 5-MeO-DMT and with relatively more activity at 5-HT_1A, but still shows strongest effects at the 5-HT₂ family of receptors.^[2]

Legal status

Dimemebfe is a Schedule I controlled substance in the US state of Alabama.^[3]

References

^ Casale JF, Hays PA. "The Characterization of 2-(5-Methoxy-1-benzofuran-3-yl)-N,N-dimethylethanamine (5-MeO-BFE) and Differentiation from its N-Ethyl Analog" (PDF). Microgram Journal. 9 (1): 39–45. Archived from the original (PDF) on 2017-05-13. Retrieved 2015-02-23.
^ Tomaszewski Z, Johnson MP, Huang X, Nichols DE (May 1992). "Benzofuran bioisosteres of hallucinogenic tryptamines". Journal of Medicinal Chemistry. 35 (11): 2061–4. doi:10.1021/jm00089a017. PMID 1534585.
^ "Alabama Senate Bill 333 - Controlled substances, Schedule I, additional synthetic controlled substances and analogue substances included in, trafficking in controlled substance analogues, requisite weight increased, Secs. 13A-12-231, 20-2-23 am'd". March 2014. Retrieved 28 September 2015.

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[1] Casale JF, Hays PA. "The Characterization of 2-(5-Methoxy-1-benzofuran-3-yl)-N,N-dimethylethanamine (5-MeO-BFE) and Differentiation from its N-Ethyl Analog" (PDF). Microgram Journal. 9 (1): 39–45. Archived from the original (PDF) on 2017-05-13. Retrieved 2015-02-23.

[2] Tomaszewski Z, Johnson MP, Huang X, Nichols DE (May 1992). "Benzofuran bioisosteres of hallucinogenic tryptamines". Journal of Medicinal Chemistry. 35 (11): 2061–4. doi:10.1021/jm00089a017. PMID 1534585.

[3] "Alabama Senate Bill 333 - Controlled substances, Schedule I, additional synthetic controlled substances and analogue substances included in, trafficking in controlled substance analogues, requisite weight increased, Secs. 13A-12-231, 20-2-23 am'd". March 2014. Retrieved 28 September 2015.

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[2]

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Legal status

See also

References