-lysine N-methyltransferase (EC 2.1.1.259)^[1][2] is an enzyme that catalyses the following chemical reaction:

3 S-adenosyl-L-methionine + -L-lysine ${\displaystyle \rightleftharpoons }$ 3 S-adenosyl-L-homocysteine + -N⁶,N⁶,N⁶-trimethyl-L-lysine

The enzyme methylates a conserved lysine in the C-terminal part of higher plant fructose-bisphosphate aldolase (EC 4.1.2.13).

Nomenclature

The systematic name of the enzyme is:

• S-adenosyl-L-methionine:(fructose-bisphosphate aldolase)-lysine N⁶-methyltransferase

Other names are:

• rubisco methyltransferase
• ribulose-bisphosphate-carboxylase/oxygenase N-methyltransferase
• ribulose-1,5-bisphosphate carboxylase/oxygenase large subunit epsilonN-methyltransferase
• S-adenosyl-L-methionine:-lysine 6-N-methyltransferase)^[2]

See also

• Methyllysine
• RuBisCO
• SET domain

References

External links

• (fructose-bisphosphate+aldolase)-lysine+N-methyltransferase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)