Viral structural protein

A viral structural protein is a viral protein that is a structural component of the mature virus.^[1]

Examples include the SARS coronavirus 3a and 7a accessory proteins.^[2]^[3]

Bacteriophage T4 structural proteins

During assembly of the bacteriophage (phage) T4 virion, the structural proteins encoded by the phage genes interact with each other in a characteristic sequence. Maintaining an appropriate balance in the amounts of each of these structural proteins produced during viral infection appears to be critical for normal phage T4 morphogenesis.^[4] Phage T4 encoded proteins that determine virion structure include major structural components, minor structural components and non-structural proteins that catalyze specific steps in the morphogenesis sequence.^[5] Phage T4 morphogenesis is divided into three independent pathways: the head, the tail and the long tail fibres as detailed by Yap and Rossman.^[6]

References

^ Viral+Structural+Proteins at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
^ Ito N, Mossel EC, Narayanan K, et al. (March 2005). "Severe acute respiratory syndrome coronavirus 3a protein is a viral structural protein". J. Virol. 79 (5): 3182–6. doi:10.1128/JVI.79.5.3182-3186.2005. PMC 548460. PMID 15709039.
^ Huang C, Ito N, Tseng CT, Makino S (August 2006). "Severe acute respiratory syndrome coronavirus 7a accessory protein is a viral structural protein". J. Virol. 80 (15): 7287–94. doi:10.1128/JVI.00414-06. PMC 1563709. PMID 16840309.
^ Floor E. Interaction of morphogenetic genes of bacteriophage T4. J Mol Biol. 1970;47(3):293-306. doi:10.1016/0022-2836(70)90303-7
^ Snustad DP. Dominance interactions in Escherichia coli cells mixedly infected with bacteriophage T4D wild-type and amber mutants and their possible implications as to type of gene-product function: catalytic vs. stoichiometric. Virology. 1968;35(4):550-563. doi:10.1016/0042-6822(68)90285-7
^ Yap ML, Rossmann MG. Structure and function of bacteriophage T4. Future Microbiol. 2014;9(12):1319-1327. doi:10.2217/fmb.14.91

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[1] Viral+Structural+Proteins at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

[pmid15709039-2] Ito N, Mossel EC, Narayanan K, et al. (March 2005). "Severe acute respiratory syndrome coronavirus 3a protein is a viral structural protein". J. Virol. 79 (5): 3182–6. doi:10.1128/JVI.79.5.3182-3186.2005. PMC 548460. PMID 15709039.

[pmid16840309-3] Huang C, Ito N, Tseng CT, Makino S (August 2006). "Severe acute respiratory syndrome coronavirus 7a accessory protein is a viral structural protein". J. Virol. 80 (15): 7287–94. doi:10.1128/JVI.00414-06. PMC 1563709. PMID 16840309.

[4] Floor E. Interaction of morphogenetic genes of bacteriophage T4. J Mol Biol. 1970;47(3):293-306. doi:10.1016/0022-2836(70)90303-7

[5] Snustad DP. Dominance interactions in Escherichia coli cells mixedly infected with bacteriophage T4D wild-type and amber mutants and their possible implications as to type of gene-product function: catalytic vs. stoichiometric. Virology. 1968;35(4):550-563. doi:10.1016/0042-6822(68)90285-7

[6] Yap ML, Rossmann MG. Structure and function of bacteriophage T4. Future Microbiol. 2014;9(12):1319-1327. doi:10.2217/fmb.14.91

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Bacteriophage T4 structural proteins

See also

References