A | B | C | D | E | F | G | H | CH | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z | 0 | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9
List of JWH cannabinoids
...The John W. Huffman research group at Clemson University synthesized over 450 cannabinoids.[1][2][3][4] Some of those are:
| Name | Class | Ki / nM at CB1 | Ki / nM at CB2 | Selectivity | Structure |
|---|---|---|---|---|---|
| JWH-004 | Naphthoylindole | 48 ± 13 | 4 ± 1.5 | CB2 (12x) | 
|
| JWH-007[5] | Naphthoylindole | 9.5 ± 4.5 | 2.9 ± 2.6 | CB2 (3.3x) | 
|
| JWH-009 | Naphthoylindole | >10000 | 141 ± 14 | CB2 (>70x) | 
|
| JWH-011 | Naphthoylindole | 
| |||
| JWH-015[5] | Naphthoylindole | 164 ± 22 | 13.8 ± 4.6 | CB2 (12x) | 
|
| JWH-016 | Naphthoylindole | 22 ± 1.5 | 4.3 ± 1.6 | CB2 (5.1x) | 
|
| JWH-018[5] | Naphthoylindole | 9 ± 5 | 2.9 ± 2.6 | CB2 (3.1x) | 
|
| JWH-019 | Naphthoylindole | 9.8 ± 2 | 5.55 ± 2 | CB2 (1.77x) | 
|
| JWH-020 | Naphthoylindole | 128 ± 17 | 205 ± 20 | CB1 (1.6x) | 
|
| JWH-030 | Naphthoylpyrrole | 87 ± 3 | 320 ± 127 | CB1 (3.7x) | 
|
| JWH-031 | Naphthoylpyrrole | 399 ± 109 | 
| ||
| JWH-032 | Naphthoylpyrrole | >10000 | >10000 | — | 
|
| JWH-033 | Naphthoylpyrrole | 666 ± 77 | 
| ||
| JWH-036 | Naphthoylpyrrole | 309 ± 11 | 
| ||
| JWH-042[6] | Naphthoylindole | >10000 | 5050 ± 192 | CB2 | 
|
| JWH-043[6] | Naphthoylindole | 1180 ± 44 | 964 ± 242 | CB2 (1.2x) | 
|
| JWH-044 | Naphthoylpyrrole | >10000 | >10000 | — | 
|
| JWH-045 | Naphthoylpyrrole | >10000 | >10000 | — | 
|
| JWH-046[6] | Naphthoylindole | 343 ± 38 | 16.3 ± 4.9 | CB2 (21x) | 
|
| JWH-047[6] | Naphthoylindole | 59 ± 3 | 3.47 ± 1.80 | CB2 (17x) | 
|
| JWH-048[6] | Naphthoylindole | 10.7 ± 1.0 | 0.49 ± 0.13 | CB2 (22x) | 
|
| JWH-049[6] | Naphthoylindole | 55.1 ± 17.0 | 32.3 ± 2.4 | CB2 (1.7x) | 
|
| JWH-050[6] | Naphthoylindole | 342 ± 6 | 526 ± 133 | CB1 (1.5x) | 
|
| JWH-051 | Dibenzopyran | 1.20 | 0.03 | CB2 (40x) | 
|
| JWH-056[7] | Dibenzopyran | >10000 | 32 ± 9 | CB2 | 
|
| JWH-057[8] | Dibenzopyran | 23 ± 7 | 2.9 ± 1.6 | CB2 (8x) | 
|
| JWH-065[7] | Dibenzopyran | 399 ± 76 | 10 ± 2 | CB2 (40x) | 
|
| JWH-070[6] | Naphthoylindole | >10000 | >10000 | 
| |
| JWH-071[6] | Naphthoylindole | 1340 ± 123 | 2940 ± 852 | CB1 (2.2x) | 
|
| JWH-072 | Naphthoylindole | 1050 ± 5.5 | 170 ± 54 | CB2 (6x) | 
|
| JWH-073 | Naphthoylindole | 8.9 ± 1.8 | 27 ± 12 | CB1 (3x) | 
|
| JWH-076[5] | Naphthoylindole | 214 ± 11 | 106 ± 46 | CB2 (2x) | 
|
| JWH-077[6] | Naphthoylindole | >10000 | >10000 | 
| |
| JWH-078[6] | Naphthoylindole | 817 ± 60 | 633 ± 116 | CB2 (1.3x) | 
|
| JWH-079[6] | Naphthoylindole | 63.0 ± 3.0 | 32.0 ± 6.0 | CB2 (2x) | 
|
| JWH-080[6] | Naphthoylindole | 8.9 ± 1.8 | 2.21 ± 1.30 | CB2 (4x) | 
|
| JWH-081[6] | Naphthoylindole | 1.2 ± 0.03 | 12.4 ± 2.2 | CB1 (10x) | 
|
| JWH-082[6] | Naphthoylindole | 5.3 ± 0.8 | 6.40 ± 0.94 | CB1 (1.2x) | 
|
| JWH-083[6] | Naphthoylindole | 106 ± 12 | 102 ± 50 | — | 
|
| JWH-091[9] (Δ8-THCP) | Dibenzopyran | 22.0 ± 3.9 | 
| ||
| JWH-093[6] | Naphthoylindole | 40.7 ± 2.8 | 59.1 ± 10.5 | CB1 (1.45x) | 
|
| JWH-094[6] | Naphthoylindole | 476 ± 67 | 97.3 ± 2.7 | CB2 (4.9x) | 
|
| JWH-095[6] | Naphthoylindole | 140 ± 4.3 | 312 ± 83 | CB1 (2.2x) | 
|
| JWH-096[6] | Naphthoylindole | 33.7 ± 2.9 | 13.3 ± 5.6 | CB2 (2.5x) | 
|
| JWH-097[6] | Naphthoylindole | 455 ± 28 | 121 ± 15 | CB2 (3.8x) | 
|
| JWH-098[6] | Naphthoylindole | 4.5 ± 0.1 | 1.9 ± 0.3 | CB2 (2.4x) | 
|
| JWH-099[6] | Naphthoylindole | 35.3 ± 9.0 | 17.8 ± 2.9 | CB2 (2x) | 
|
| JWH-100[6] | Naphthoylindole | 381 ± 102 | 155 ± 74 | CB2 (2.5x) | 
|
| JWH-102[7] | Dibenzopyran | 7.9 ± 0.9 | 5.2 ± 2.0 | CB2 (1.5x) | 
|
| JWH-103[7] | Dibenzopyran | 28 ± 3 | 23 ± 7 | CB2 (1.2x) | 
|
| JWH-116[10] | Naphthoylindole | 52 ± 5 | 
| ||
| JWH-120[5] | Naphthoylindole | 1054 ± 31 | 6.1 ± 0.7 | CB2 (173x) | 
|
| JWH-122[10] | Naphthoylindole | 0.69 ± 0.05 | 1.2 ± 1.2 | — | 
|
| JWH-124 (Δ8-Parahexyl) | Dibenzopyran | 41.0 ± 3.8 | 
| ||
| JWH-130 (Δ8-THCB) | Dibenzopyran | 65.0 ± 13 | 
| ||
| JWH-133[7] | Dibenzopyran | 677 ± 132 | 3.4 ± 1.0 | CB2 (200x) | 
|
| JWH-138[11] | Dibenzopyran | 8.5 ± 1.4 | 
| ||
| JWH-139[12] | Dibenzopyran | 2290 ± 505 | 14 ± 10 | CB2 (164x) | 
|
| JWH-142[7] | Dibenzopyran | 529 ± 49 | 35 ± 14 | CB2 (15x) | 
|
| JWH-143[7] | Dibenzopyran | 924 ± 104 | 65 ± 8 | CB2 (14x) | 
|
| JWH-145[13] | Naphthoylpyrrole | 14 ± 2 | 6.4 ± 0.4 | CB2 (2.2x) | 
|
| JWH-146[13] | Naphthoylpyrrole | 21 ± 2 | 62 ± 5 | CB2 (3.0x) | 
|
| JWH-147[13] | Naphthoylpyrrole | 11 ± 1 | 7.1 ± 0.2 | CB2 (1.5x) | 
|
| JWH-148[5] | Naphthoylindole | 123 ± 8 | 14.0 ± 1.0 | CB2 (8x) | 
|
| JWH-149[5] | Naphthoylindole | 5.0 ± 2.1 | 0.73 ± 0.03 | CB2 (6.8x) | 
|
| JWH-150[13] | Naphthoylpyrrole | 60 ± 1 | 15 ± 2 | CB2 (4x) | 
|
| JWH-151[5] | Naphthoylindole | >10000 | 30 ± 1.1 | CB2 (>333x) | 
|
| JWH-153[5] | Naphthoylindole | 250 ± 24 | 11 ± 0.5 | CB2 (23x) | 
|
| JWH-156[13] | Naphthoylpyrrole | 404 ± 18 | 104 ± 18 | CB2 (4x) | 
|
| JWH-159[5] | Naphthoylindole | 45 ± 1 | 10.4 ± 1.4 | CB2 (4.3x) | 
|
| JWH-160[5] | Naphthoylindole | 1568 ± 201 | 441 ± 110 | CB2 (3.6x) | 
|
| JWH-161 | Dibenzopyran hybrid | 19.0 | 
| ||
| JWH-163[5] | Naphthoylindole | 2358 ± 215 | 138 ± 12 | CB2 (17x) | 
|
| JWH-164[5] | Naphthoylindole | 6.6 ± 0.7 | 6.9 ± 0.2 | — | 
|
| JWH-165[5] | Naphthoylindole | 204 ± 26 | 71 ± 8 | CB2 (2.9x) | 
|
| JWH-166[5] | Naphthoylindole | 44 ± 10 | 1.9 ± 0.08 | CB2 (23x) | 
|
| JWH-167 | Phenylacetylindole | 90 ± 17 | 159 ± 14 | CB1 (1.77x) | 
|
| JWH-171 | Hydrocarbon | 51 | 
| ||
| JWH-175[10] | Naphthylmethylindole | 22 ± 2 | 
| ||
| JWH-176[10] | Hydrocarbon | 26 ± 4 | 
| ||
| JWH-180[5] | Naphthoylindole | 26 ± 2 | 9.6 ± 2.0 | CB2 (2.7x) | 
|
| JWH-181[5] | Naphthoylindole | 1.3 ± 0.1 | 0.62 ± 0.04 | CB2 (2.1x) | 
|
| JWH-182[5] | Naphthoylindole | 0.65 ± 0.03 | 1.1 ± 0.1 | CB1 (1.7x) | 
|
| JWH-184[10] | Naphthylmethylindole | 23 ± 6 | 
| ||
| JWH-185[10] | Naphthylmethylindole | 17 ± 3 | 
| ||
| JWH-186[14] | Dibenzopyran | 187 ± 23 | 5.6 ± 1.7 | CB2 (33x) | 
|
| JWH-187[14] | Dibenzopyran | 84 ± 16 | 3.4 ± 0.5 | CB2 (25x) | 
|
| JWH-188[14] | Dibenzopyran | 270 ± 58 | 18 ± 2 | CB2 (15x) | 
|
| JWH-189[5] | Naphthoylindole | 52 ± 2 | 12 ± 0.8 | CB2 (4.3x) | 
|
| JWH-190[14] | Dibenzopyran | 8.8 ± 1.4 | 1.6 ± 0.03 | CB2 (5.5x) | 
|
| JWH-191[14] | Dibenzopyran | 1.8 ± 0.3 | 0.52 ± 0.03 | CB2 (3.5x) | 
|
| JWH-192[10] | Naphthylmethylindole | 41 ± 13 | 
| ||
| JWH-193[10] | Naphthoylindole | 6 ± 1 | 
| ||
| JWH-194[10] | Naphthylmethylindole | 127 ± 19 | 
| ||
| JWH-195[10] | Naphthylmethylindole | 113 ± 28 | 
| ||
| JWH-196[10] | Naphthylmethylindole | 151 ± 18 | 
| ||
| JWH-197[10] | Naphthylmethylindole | 323 ± 98 | 
| ||
| JWH-198[10] | Naphthoylindole | 10 ± 2 | 
| ||
| JWH-199[10] | Naphthylmethylindole | 20 ± 2 | 
| ||
| JWH-200[10] | Naphthoylindole | 42 ± 5 | 
| ||
| JWH-201[15] | Phenylacetylindole | 1064 ± 21 | 444 ± 14 | CB2 (2.4x) | 
|
| JWH-202[15] | Phenylacetylindole | 1678 ± 63 | 645 ± 6 | CB2 (2.6x) | 
|
| JWH-203[15] | Phenylacetylindole | 8.0 ± 0.9 | 7.0 ± 1.3 | — | 
|
| JWH-204[15] | Phenylacetylindole | 13 ± 1 | 25 ± 1 | CB1 (1.9x) | 
|
| JWH-205[15] | Phenylacetylindole | 124 ± 23 | 180 ± 9 | CB1 (1.45x) | 
|
| JWH-206[15] | Phenylacetylindole | 389 ± 25 | 498 ± 37 | CB1 (1.28x) | 
|
| JWH-207[15] | Phenylacetylindole | 1598 ± 134 | 3723 ± 10 | CB1 (2.33x) | 
|
| JWH-208[15] | Zdroj:https://en.wikipedia.org?pojem=List_of_JWH_cannabinoids