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VPS52 | |||||||||||||||||||||||||||||||||||||||||||||||||||
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Identifiers | |||||||||||||||||||||||||||||||||||||||||||||||||||
Aliases | VPS52, ARE1, SAC2, SACM2L, dJ1033B10.5, GARP complex subunit, VPS52 subunit of GARP complex | ||||||||||||||||||||||||||||||||||||||||||||||||||
External IDs | OMIM: 603443; MGI: 1330304; HomoloGene: 5756; GeneCards: VPS52; OMA:VPS52 - orthologs | ||||||||||||||||||||||||||||||||||||||||||||||||||
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Wikidata | |||||||||||||||||||||||||||||||||||||||||||||||||||
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Vacuolar protein sorting-associated protein 52 homolog is a protein that in humans is encoded by the VPS52 gene.[5][6]
This gene encodes a protein that is similar to the yeast suppressor of actin mutations 2 gene. The yeast protein forms a subunit of the tetrameric Golgi-associated retrograde protein complex that is involved in vesicle trafficking from both early and late endosomes, back to the trans-Golgi network. This gene is located on chromosome 6 in a head-to-head orientation with the gene encoding ribosomal protein S18.[6]
References
- ^ a b c ENSG00000206286, ENSG00000223501, ENSG00000224455, ENSG00000225590, ENSG00000223618, ENSG00000228425 GRCh38: Ensembl release 89: ENSG00000236014, ENSG00000206286, ENSG00000223501, ENSG00000224455, ENSG00000225590, ENSG00000223618, ENSG00000228425 – Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000024319 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ Walter L, Gunther E (Dec 1998). "Identification of a novel highly conserved gene in the centromeric part of the major histocompatibility complex". Genomics. 52 (3): 298–304. doi:10.1006/geno.1998.5463. PMID 9790748.
- ^ a b "Entrez Gene: VPS52 vacuolar protein sorting 52 homolog (S. cerevisiae)".
Further reading
- Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
- Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
- Stephens R, Horton R, Humphray S, et al. (1999). "Gene organisation, sequence variation and isochore structure at the centromeric boundary of the human MHC". J. Mol. Biol. 291 (4): 789–99. doi:10.1006/jmbi.1999.3004. PMID 10452889.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Mungall AJ, Palmer SA, Sims SK, et al. (2003). "The DNA sequence and analysis of human chromosome 6". Nature. 425 (6960): 805–11. Bibcode:2003Natur.425..805M. doi:10.1038/nature02055. PMID 14574404.
- Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
- Liewen H, Meinhold-Heerlein I, Oliveira V, et al. (2005). "Characterization of the human GARP (Golgi associated retrograde protein) complex". Exp. Cell Res. 306 (1): 24–34. doi:10.1016/j.yexcr.2005.01.022. PMID 15878329.
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