Sitafloxacin

Clinical data
Routes of administration	Oral
ATC code	J01MA21 (WHO)
Legal status
Legal status	In general: ℞ (Prescription only)
Identifiers
IUPAC name 7-2.4heptan-6-yl-8-chloro-6-fluoro-1-(2S)-2-fluorocyclopropyl-4-oxoquinoline-3-carboxylic acid
CAS Number	127254-12-0 N
PubChem CID	461399
ChemSpider	405945 Y
UNII	3GJC60U4Q8
KEGG	D02475 N
ChEMBL	ChEMBL108821 Y
CompTox Dashboard (EPA)	DTXSID5048847
Chemical and physical data
Formula	C19H18ClF2N3O3
Molar mass	409.82 g·mol−1
3D model (JSmol)	Interactive image
SMILES FC@H5CC@H5N2/C=C(/C(=O)O)C(=O)c1cc(F)c(c(Cl)c12)N4CC@@H(N)C3(CC3)C4
InChI InChI=1S/C19H18ClF2N3O3/c20-14-15-8(17(26)9(18(27)28)5-25(15)12-4-10(12)21)3-11(22)16(14)24-6-13(23)19(7-24)1-2-19/h3,5,10,12-13H,1-2,4,6-7,23H2,(H,27,28)/t10-,12+,13+/m0/s1 Y Key:PNUZDKCDAWUEGK-CYZMBNFOSA-N Y
NY (what is this?)  (verify)

Sitafloxacin (INN; also called DU-6859a) is a fluoroquinolone antibiotic^[1] that shows promise in the treatment of Buruli ulcer. The molecule was identified by Daiichi Sankyo Co., which brought ofloxacin and levofloxacin to the market. Sitafloxacin is currently marketed in Japan by Daiichi Sankyo under the tradename Gracevit.^{[citation needed]}

See alsoedit

• Quinolone

Referencesedit

Further readingedit

• Keating GM (April 2011). "Sitafloxacin: in bacterial infections". Drugs. 71 (6): 731–44. doi:10.2165/11207380-000000000-00000. PMID 21504249. S2CID 195688876.

External linksedit

• (in Japanese) Gracevit グレースビット (PDF) Daiichi Sankyo Co. January 2008.

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