Salvia dominica

Salvia dominica
Scientific classification
Kingdom:	Plantae
Clade:	Tracheophytes
Clade:	Angiosperms
Clade:	Eudicots
Clade:	Asterids
Order:	Lamiales
Family:	Lamiaceae
Genus:	Salvia
Species:	S. dominica
Binomial name
	Salvia dominica; L.
Synonyms
	Salvia graveolens Vahl

Salvia dominica (Dominica sage, in Arabic ( Maru = مرو or "Khowwekha" = خويخة ), in (Hebrew: מרווה, marva) is a strong-scented perennial shrub found throughout the eastern Mediterranean, especially Jordan^[1] Israel,^[2] Lebanon and Syria. The branched inflorescence is one of several salvias thought to have inspired the design of the menorah. It grows to about 1 meter in height and width, and blooms in spring or early summer with pale yellow and white flowers in delicate whorls.^[3]

Biological properties

A group of Italian and Jordanian researchers isolated twenty-four new sesterterpenes, some of them with interesting biological activity due to their interaction with tubulin-tyrosine ligase (TTL), an enzyme involved in the tyrosination cycle of the C-terminus of tubulin, and inhibit TTL activity in cancer cells.^[4]

References

^ Field Guide of Wild Flower of Jordan and Neighbouring Countries by Dawud Al-Eisawi
^ Flowers in Israel
^ Clebsch, Betsy; Barner, Carol D. (2003). The New Book of Salvias. Timber Press. p. 112. ISBN 978-0-88192-560-9.
^ Dal Piaz F; Vassallo A; Lepore L; Tosco A; Bader A; De Tommasi N (June 2009). "Sesterterpenes as tubulin tyrosine ligase inhibitors. First insight of structure-activity relationships and discovery of new lead". J. Med. Chem. 52 (12): 3814–28. doi:10.1021/jm801637f. hdl:11563/19141. PMID 19459643.

Zdroj:https://en.wikipedia.org?pojem=Salvia_dominica
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[1] Field Guide of Wild Flower of Jordan and Neighbouring Countries by Dawud Al-Eisawi

[2] Flowers in Israel

[Clebsch-3] Clebsch, Betsy; Barner, Carol D. (2003). The New Book of Salvias. Timber Press. p. 112. ISBN 978-0-88192-560-9.

[4] Dal Piaz F; Vassallo A; Lepore L; Tosco A; Bader A; De Tommasi N (June 2009). "Sesterterpenes as tubulin tyrosine ligase inhibitors. First insight of structure-activity relationships and discovery of new lead". J. Med. Chem. 52 (12): 3814–28. doi:10.1021/jm801637f. hdl:11563/19141. PMID 19459643.

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