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A ring forming reaction or ring-closing reaction in organic chemistry is a general term for a variety of reactions that introduce one or more rings into a molecule. A heterocycle forming reaction is such a reaction that introduces a new heterocycle.[1][2] Important classes of ring forming reactions include annulations[3] and cycloadditions.
Named ring forming reactions
Named ring forming reactions include (not exhaustive):
- Azide-alkyne Huisgen cycloaddition
- Bischler–Napieralski reaction
- Bucherer carbazole synthesis
- Danheiser annulation
- Dieckmann condensation
- Diels–Alder reaction
- Feist–Benary synthesis
- Fiesselmann thiophene synthesis
- Fischer indole synthesis
- Gewald reaction
- Hantzsch pyridine synthesis
- Larock indole synthesis
- Paal–Knorr synthesis
- Pictet–Spengler reaction
- Pomeranz–Fritsch reaction
- Ring-closing metathesis
- Robinson annulation
- Skraup reaction
References
- ^ IUPAC, Compendium of Chemical Terminology, 2nd ed. (the "Gold Book") (1997). Online corrected version: (1995) "Heterocyclic compounds". doi:10.1351/goldbook.H02798
- ^ Katritzky, A. R.; Pozharskii, A. F. (2000). Handbook of Heterocyclic Chemistry (2nd ed.). Academic Press. ISBN 0080429882.
- ^ IUPAC, Compendium of Chemical Terminology, 2nd ed. (the "Gold Book") (1997). Online corrected version: (2006–) "annulation". doi:10.1351/goldbook.A00367
Further reading
- Michael B. Smith & Jerry March, 2007, "March's Advanced Organic Chemistry: Reactions, Mechanisms, and Structure," 6th Ed., New York, NY, USA:Wiley & Sons, ISBN 0470084944, see , accessed 19 June 2015.
- László Kürti & Barbara Czakó, 2005, "Strategic Applications of Named Reactions in Organic Synthesis: Background and Detailed Mechanisms, Amsterdam, NH, NLD:Elsevier Academic Press, 2005ISBN 0124297854, see , accessed 19 June 2015.
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