Receptor protein serine/threonine kinase

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Receptor protein serine/threonine kinase
Receptor protein serine/threonine kinase
Identifiers
EC no.	2.7.11.30
CAS no.	146702-86-5
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
PMC
Search
PMC	articles
PubMed	articles
NCBI	proteins

Receptor protein serine/threonine kinase
Receptor protein serine/threonine kinase
Identifiers
Symbol	Receptor protein serine/threonine kinase
Membranome	3

Receptor protein serine/threonine kinases (EC 2.7.11.30) are enzyme-linked receptors that belong to protein-serine/threonine kinases. The systematic name of this enzyme class is ATP: phosphotransferase. Proteins from this group participate in 7 metabolic pathways: MAPK signaling pathway, cytokine-cytokine receptor interaction, TGF beta signaling pathway, adherens junction, colorectal cancer, pancreatic cancer, and chronic myeloid leukemia.

Links

Receptor protein serine/threonine kinases in IUPHAR Guide to Pharmacology

References

Wrana JL, Attisano L, Wieser R, Ventura F, Massague J (1994). "Mechanism of activation of the TGF-beta receptor". Nature. 370 (6488): 341–7. Bibcode:1994Natur.370..341W. doi:10.1038/370341a0. PMID 8047140. S2CID 4344481.
Massague J, Chen YG (2000). "Controlling TGF-beta signaling". Genes Dev. 14 (6): 627–44. PMID 10733523.
Lechleider RJ; Hemmati, P; Larisch-Bloch, S; Ajmera, R; Roberts, AB; Lechleider, RJ (1997). "Characterization of functional domains within Smad4/DPC4". J. Biol. Chem. 272 (21): 13690–6. doi:10.1074/jbc.272.21.13690. PMID 9153220.

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