Polycentric chromosome

In genetics, a polycentric chromosome is any chromosome featuring multiple centromeres.^[1] Polycentric chromosomes are produced by chromosomal aberrations such as deletion, duplication, or translocation.^{[citation needed]} Polycentric chromosomes usually result in the death of the cell because polycentric chromosomes may fail to move to opposite poles of spindle fiber during anaphase. As a result, the chromosome is fragmented, which causes the death of the cell. In some algae, such as Spirogyra, polycentric chromosomes appear normally.^[2] They also occur in the sedge, Luzula.^[3]

References

^ Neumann P, Navrátilová A, Schroeder-Reiter E, Koblížková A, Steinbauerová V, Chocholová E, et al. (2012-06-21). "Stretching the rules: monocentric chromosomes with multiple centromere domains". PLOS Genetics. 8 (6): e1002777. doi:10.1371/journal.pgen.1002777. PMC 3380829. PMID 22737088.
^ Godward MB (April 1954). "The 'Diffuse' Centromere or Polycentric Chromosomes in Spirogyra". Annals of Botany. 18 (2): 143–144. doi:10.1093/oxfordjournals.aob.a083387.
^ D. Lewis (1986). "Leonard Francis La Cour 28 July 1907–3 November 1984". Biographical Memoirs of Fellows of the Royal Society. 32 (32): 368. doi:10.1098/rsbm.1986.0011.

This genetics article is a stub. You can help Wikipedia by expanding it.

Zdroj:https://en.wikipedia.org?pojem=Polycentric_chromosome
Text je dostupný za podmienok Creative Commons Attribution/Share-Alike License 3.0 Unported; prípadne za ďalších podmienok. Podrobnejšie informácie nájdete na stránke Podmienky použitia.

[1] Neumann P, Navrátilová A, Schroeder-Reiter E, Koblížková A, Steinbauerová V, Chocholová E, et al. (2012-06-21). "Stretching the rules: monocentric chromosomes with multiple centromere domains". PLOS Genetics. 8 (6): e1002777. doi:10.1371/journal.pgen.1002777. PMC 3380829. PMID 22737088.

[2] Godward MB (April 1954). "The 'Diffuse' Centromere or Polycentric Chromosomes in Spirogyra". Annals of Botany. 18 (2): 143–144. doi:10.1093/oxfordjournals.aob.a083387.

[3] D. Lewis (1986). "Leonard Francis La Cour 28 July 1907–3 November 1984". Biographical Memoirs of Fellows of the Royal Society. 32 (32): 368. doi:10.1098/rsbm.1986.0011.

[1]

[2]

[3]