DEFB119

DEFB119
Identifiers
Aliases	DEFB119, DEFB-19, DEFB-20, DEFB120, ESC42-RELA, ESC42-RELB, DEFB20, defensin beta 119
External IDs	OMIM: 615997; MGI: 2385955; HomoloGene: 17045; GeneCards: DEFB119; OMA:DEFB119 - orthologs
Gene location (Human)
Chr.	Chromosome 20 (human)
End	31,390,590 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	152,422,232 bp
RNA expression pattern
	Top expressed in
	corpus epididymis; ; right testis; ; left testis; ; testicle; ; tail of epididymis; ; buccal mucosa cell; ; caput epididymis; ; sperm; ; right coronary artery; ; retinal pigment epithelium;
	Top expressed in
	Gonadal ridge; ; seminiferous tubule; ; spermatocyte; ; embryo; ; spermatid; ; cumulus cell; ; efferent ductule; ; epithelium of seminiferous tubule of testis; ; Sertoli cell; ; morula;
	More reference expression data
	n/a
Gene ontology
Molecular function	lipopolysaccharide binding;
Cellular component	extracellular region; cell surface;
Biological process	defense response to bacterium; defense response; innate immune response;
	Sources:Amigo / QuickGO
Orthologs
	245932
	246700
	ENSG00000180483
	ENSMUSG00000050645
	Q8N690
	Q8K3I8
	NM_001271209; NM_153289; NM_153323
	NM_145157
	NP_001258138; NP_695021; NP_697018
	NP_660139
	Wikidata
View/Edit Human	View/Edit Mouse

Beta-defensin 119 is a protein that in humans is encoded by the DEFB119 gene.^[5]^[6]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000180483 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000050645 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Schutte BC, Mitros JP, Bartlett JA, Walters JD, Jia HP, Welsh MJ, Casavant TL, McCray PB Jr (Feb 2002). "Discovery of five conserved beta -defensin gene clusters using a computational search strategy". Proc Natl Acad Sci U S A. 99 (4): 2129–33. Bibcode:2002PNAS...99.2129S. doi:10.1073/pnas.042692699. PMC 122330. PMID 11854508.
^ "Entrez Gene: DEFB119 defensin, beta 119".

Lehrer RI, Ganz T (2002). "Defensins of vertebrate animals". Curr. Opin. Immunol. 14 (1): 96–102. doi:10.1016/S0952-7915(01)00303-X. PMID 11790538.
Raj PA, Dentino AR (2002). "Current status of defensins and their role in innate and adaptive immunity". FEMS Microbiol. Lett. 206 (1): 9–18. doi:10.1111/j.1574-6968.2002.tb10979.x. PMID 11786250.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Clark HF, Gurney AL, Abaya E, et al. (2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC 403697. PMID 12975309.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Yamamoto M, Matsui Y (2003). "Testis-specific expression of a novel mouse defensin-like gene, Tdl". Mech. Dev. 116 (1–2): 217–21. doi:10.1016/S0925-4773(02)00144-2. PMID 12128228. S2CID 15160486.
Deloukas P, Matthews LH, Ashurst J, et al. (2002). "The DNA sequence and comparative analysis of human chromosome 20". Nature. 414 (6866): 865–71. Bibcode:2001Natur.414..865D. doi:10.1038/414865a. PMID 11780052.

This article on a gene on human chromosome 20 is a stub. You can help Wikipedia by expanding it.

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[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000180483 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000050645 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid11854508-5] Schutte BC, Mitros JP, Bartlett JA, Walters JD, Jia HP, Welsh MJ, Casavant TL, McCray PB Jr (Feb 2002). "Discovery of five conserved beta -defensin gene clusters using a computational search strategy". Proc Natl Acad Sci U S A. 99 (4): 2129–33. Bibcode:2002PNAS...99.2129S. doi:10.1073/pnas.042692699. PMC 122330. PMID 11854508.

[entrez-6] "Entrez Gene: DEFB119 defensin, beta 119".

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References

Further reading