ARR3

ARR3
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1XEH, 2A34
Identifiers
Aliases	ARR3, ARRX, cArr, arrestin 3 retinal (X-arrestin), arrestin 3, MYP26
External IDs	OMIM: 301770 MGI: 2159617 HomoloGene: 3182 GeneCards: ARR3
Gene location (Human)
Chr.	X chromosome (human)
End	70,281,840 bp
Gene location (Mouse)
Chr.	X chromosome (mouse)
End	99,662,099 bp
RNA expression pattern
	Top expressed in
	retina; ; retinal pigment epithelium; ; sural nerve; ; stromal cell of endometrium; ; rectum; ; monocyte; ; skin of abdomen; ; lymph node; ; skeletal muscle tissue; ; transverse colon;
	Top expressed in
	morula; ; retinal pigment epithelium; ; superior frontal gyrus; ; outer nuclear layer; ; cerebellar cortex; ; olfactory bulb; ; hippocampus proper; ; digastric muscle; ; carotid body; ; spleen;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	phosphoprotein binding; opsin binding; protein binding; G protein-coupled receptor binding;
Cellular component	photoreceptor inner segment; cytoplasm; photoreceptor outer segment; synapse;
Biological process	regulation of protein phosphorylation; endocytosis; signal transduction; visual perception; response to stimulus; G protein-coupled receptor internalization;
	Sources:Amigo / QuickGO
Orthologs
	407
	170735
	ENSG00000120500
	ENSMUSG00000060890
	P36575
	Q9EQP6
	NM_004312
	NM_133205
	NP_004303
	NP_573468
	Wikidata
View/Edit Human	View/Edit Mouse

Arrestin-C, also known as retinal cone arrestin-3, is a protein that in humans is encoded by the ARR3 gene.^[5]^[6]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000120500 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000060890 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Murakami A, Yajima T, Sakuma H, McLaren MJ, Inana G (Dec 1993). "X-arrestin: a new retinal arrestin mapping to the X chromosome". FEBS Lett. 334 (2): 203–9. doi:10.1016/0014-5793(93)81712-9. PMID 8224247.
^ "Entrez Gene: ARR3 arrestin 3, retinal (X-arrestin)".

Craft CM, Whitmore DH, Wiechmann AF (1994). "Cone arrestin identified by targeting expression of a functional family". J. Biol. Chem. 269 (6): 4613–9. doi:10.1016/S0021-9258(17)41820-5. PMID 8308033.
Sakuma H, Inana G, Murakami A, et al. (1996). "Immunolocalization of X-arrestin in human cone photoreceptors". FEBS Lett. 382 (1–2): 105–10. doi:10.1016/0014-5793(96)00163-9. PMID 8612728.
ter Haar E, Musacchio A, Harrison SC, Kirchhausen T (1998). "Atomic structure of clathrin: a beta propeller terminal domain joins an alpha zigzag linker". Cell. 95 (4): 563–73. doi:10.1016/S0092-8674(00)81623-2. PMC 4428171. PMID 9827808.
Orsini MJ, Benovic JL (1999). "Characterization of dominant negative arrestins that inhibit beta2-adrenergic receptor internalization by distinct mechanisms". J. Biol. Chem. 273 (51): 34616–22. doi:10.1074/jbc.273.51.34616. PMID 9852134.
Sakuma H, Murakami A, Fujimaki T, Inana G (1999). "Isolation and characterization of the human X-arrestin gene". Gene. 224 (1–2): 87–95. doi:10.1016/S0378-1119(98)00510-1. PMID 9931451.
John SK, Smith JE, Aguirre GD, Milam AH (2000). "Loss of cone molecular markers in rhodopsin-mutant human retinas with retinitis pigmentosa". Mol. Vis. 6: 204–15. PMID 11063754.
Chen Z, Dupré DJ, Le Gouill C, et al. (2002). "Agonist-induced internalization of the platelet-activating factor receptor is dependent on arrestins but independent of G-protein activation. Role of the C terminus and the (D/N)PXXY motif". J. Biol. Chem. 277 (9): 7356–62. doi:10.1074/jbc.M110058200. PMID 11729201.
Kim YM, Barak LS, Caron MG, Benovic JL (2002). "Regulation of arrestin-3 phosphorylation by casein kinase II". J. Biol. Chem. 277 (19): 16837–46. doi:10.1074/jbc.M201379200. PMID 11877451.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Zhu X, Li A, Brown B, et al. (2002). "Mouse cone arrestin expression pattern: light induced translocation in cone photoreceptors". Mol. Vis. 8: 462–71. PMID 12486395.
Zhang H, Cuenca N, Ivanova T, et al. (2003). "Identification and light-dependent translocation of a cone-specific antigen, cone arrestin, recognized by monoclonal antibody 7G6". Invest. Ophthalmol. Vis. Sci. 44 (7): 2858–67. doi:10.1167/iovs.03-0072. hdl:10045/13046. PMID 12824223.
Krishnamurthy H, Galet C, Ascoli M (2004). "The association of arrestin-3 with the follitropin receptor depends on receptor activation and phosphorylation". Mol. Cell. Endocrinol. 204 (1–2): 127–40. doi:10.1016/S0303-7207(03)00088-1. PMID 12850288. S2CID 25222855.
Zhu X, Brown B, Li A, et al. (2003). "GRK1-dependent phosphorylation of S and M opsins and their binding to cone arrestin during cone phototransduction in the mouse retina". J. Neurosci. 23 (14): 6152–60. doi:10.1523/JNEUROSCI.23-14-06152.2003. PMC 6740345. PMID 12853434.
Ermakova NA, Alekberova ZS, Prokaeva TB (2004). "Autoimmunity to S-Antigen and Retinal Vasculitis in Patients with Behçet's Disease". Adamantiades-Behçet's Disease. Advances in Experimental Medicine and Biology. Vol. 528. pp. 279–81. doi:10.1007/0-306-48382-3_56. ISBN 978-0-306-47757-7. PMID 12918707.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Ross MT, Grafham DV, Coffey AJ, et al. (2005). "The DNA sequence of the human X chromosome". Nature. 434 (7031): 325–37. Bibcode:2005Natur.434..325R. doi:10.1038/nature03440. PMC 2665286. PMID 15772651.
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.
Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931.

External links

Human ARR3 genome location and ARR3 gene details page in the UCSC Genome Browser.

This article on a gene on the human X chromosome and/or its associated protein is a stub. You can help Wikipedia by expanding it.

Zdroj:https://en.wikipedia.org?pojem=ARR3
Text je dostupný za podmienok Creative Commons Attribution/Share-Alike License 3.0 Unported; prípadne za ďalších podmienok. Podrobnejšie informácie nájdete na stránke Podmienky použitia.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000120500 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000060890 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid8224247-5] Murakami A, Yajima T, Sakuma H, McLaren MJ, Inana G (Dec 1993). "X-arrestin: a new retinal arrestin mapping to the X chromosome". FEBS Lett. 334 (2): 203–9. doi:10.1016/0014-5793(93)81712-9. PMID 8224247.

[entrez-6] "Entrez Gene: ARR3 arrestin 3, retinal (X-arrestin)".

[1]

[2]

[3]

[4]

[5]

[6]

v t e Protein: cell membrane proteins (other than Cell surface receptor, enzymes, and cytoskeleton)
Arrestin	SAG ARRB1 ARRB2 ARR3
Membrane-spanning 4A	MS4A1 MS4A2 MS4A3 MS4A4A MS4A4E MS4A5 MS4A6A MS4A6E MS4A7 MS4A8B MS4A9 MS4A10 MS4A12 MS4A13 MS4A14 MS4A15 MS4A18
Myelin	Myelin basic protein PMP2 Myelin proteolipid protein PLP1 Myelin oligodendrocyte glycoprotein Myelin-associated glycoprotein Myelin protein zero
Pulmonary surfactant	Pulmonary surfactant-associated protein B Pulmonary surfactant-associated protein C
Tetraspanin	TSPAN1 TSPAN2 TSPAN3 TSPAN4 TSPAN5 TSPAN6 TSPAN7 TSPAN8 TSPAN9 TSPAN10 TSPAN11 TSPAN12 TSPAN13 TSPAN14 TSPAN15 TSPAN16 TSPAN17 TSPAN18 TSPAN19 TSPAN20 TSPAN21 TSPAN22 TSPAN23 TSPAN24 TSPAN25 TSPAN26 TSPAN27 TSPAN28 TSPAN29 TSPAN30 TSPAN31 TSPAN32 TSPAN33 TSPAN34
Other/ungrouped	Calnexin LDL-receptor-related protein-associated protein Neurofibromin 2 Presenilin PSEN1 PSEN2 HFE Phospholipid transfer proteins Dysferlin STRC OTOF
see also other cell membrane protein disorders

See also

References

Further reading

External links